i'm usually fine with minor, default X11 settings like fonts and sizes. after recent debian update (debian/testing to be precise) default cursor changed to something about 3x bigger than previous one. it looked just awful and attracted way to much attention than mouse cursor should. since i'm using fluxbox, and apps from many different environments, i've ended up reconfiguring it from the command line:
apt-get install xcursor-themes update-alternatives --config x-cursor-theme
the one i'm used to is /etc/X11/cursors/core.theme – small, simple and just fine. the whole operation is trivial, but it takes a bit time if you do not know The Answer. hope this will save you some time.